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P3-PDA-C1432Active studySynthetic mock data

RECIST-style longitudinal research workspace

Progression-free survival at 32 weeks

Phase

III

Enrollment

314/380

83%

Sites

18

Readout

2026-09

Waterfall — best % change in target-lesion sum (P3-PDA-C1432)

Per-subject best response from baseline. Sorted descending. Reference lines at PR (-30%) and PD (+20%) thresholds.

CR (0)PR (3)SD (3)PD (0)
-100%-75%-50%-25%0%25%50%PR threshold -30%PD threshold +20%James O'Connor (P3-1432-022) — -4.1% — Stable disease-41432-022Linda Sørensen (P3-1432-044) — -8.5% — Stable disease-81432-044Aisha Patel (P3-1432-031) — -14.3% — Stable disease-141432-031David Marquez (P3-1432-051) — -37.9% — Partial response-381432-051Maria Alvarez (P3-1432-018) — -46.7% — Partial response-471432-018Robert Chen (P3-1432-039) — -66.3% — Partial response-661432-039% change
6 subjects, sorted by best responseDrill into study →

Protocol summary

Sponsor
Vanq Oncology Cooperative
Status
active
Start date
2024-08-12
Arms
2
Sites
18
Primary endpoint
Progression-free survival at 32 weeks

Endpoints assigned to this study

Subjects in P3-PDA-C1432

6 subjects with serial RECIST measurements

s-1432-018

Maria Alvarez

Arm A · 4 target lesions

PR

s-1432-022

James O'Connor

Arm A · 3 target lesions

SD

s-1432-031

Aisha Patel

Arm B · 2 target lesions

SD

s-1432-039

Robert Chen

Arm A · 3 target lesions

PR

s-1432-044

Linda Sørensen

Arm B · 2 target lesions

SD

s-1432-051

David Marquez

Arm A · 3 target lesions

PR

Featured subject

Maria Alvarez · s-1432-018 · MRN 6024118

Open full subject record →

RECIST 1.1 — Target lesions

Serial measurements (mm) and per-visit response

Sum-of-diameters; % from baseline (PR ≤ -30%); % from nadir (PD ≥ +20% absolute ≥ 5 mm)

Best response: PR
LesionModality
Baseline2025-09-04
Wk 82025-10-30
Wk 162025-12-25
Wk 242026-02-19
Wk 322026-04-16

Pancreas head

Primary lesion, abuts SMV

CT4236282422

Liver segment 6

Solitary metastasis

CT2824181514

Liver segment 8

CT1916121010

Para-aortic node

Short-axis ≥15 mm at baseline

CT1614111010
Sum of diametersmm10590695956
% from baseline0.0%-14.3%-34.3%-43.8%-46.7%
% from nadir0.0%0.0%0.0%0.0%0.0%
RECIST responseNESDPRPRPR

Non-target lesions

Per-visit qualitative status (presence / absence / equivocal / new)

LesionBaselineWk 8Wk 16Wk 24Wk 32
Peritoneal strandingpresentpresentequivocalabsentabsent
Celiac node (sub-cm)presentpresentpresentpresentpresent

Cohorts in P3-PDA-C1432

Arm A — escalation responders

n = 142

Status: locked · updated 2026-04-21

Arm B — standard-of-care

n = 124

Status: locked · updated 2026-04-21

Cross-links

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