Cohort · P2-CRC-D0918Active studySynthetic mock data

ctDNA MRD-negative sub-cohort

Owner ML · last updated 2026-04-12

Size

23

Status

draft

Inclusion criteria

2

Exclusion criteria

1

Definition

Inclusion

  • +Stage III CRC s/p curative resection
  • +Undetectable ctDNA at week 4 post-op

Exclusion

  • Inadequate surgical margin
draftP2-CRC-D0918Owner MLLast updated 2026-04-12

Enrollment over time

012230w4w8w12w16w

From wk 0 (n=0) to wk 16 (n=23)

Subjects in cohort (8)

SubjectMRNAge / SexSiteEnrolledStatus
CRC-MRDN-001 Maria AlvarezMRN 602540048 / FSite 03 — Chicago2025-10-04withdrawn
CRC-MRDN-002 Henry MüllerMRN 602540151 / MSite 09 — Munich2025-10-09active
CRC-MRDN-003 Rachel SørensenMRN 602540254 / FSite 12 — Singapore2025-10-14active
CRC-MRDN-004 Robert AdebayoMRN 602540357 / MSite 14 — Boston2025-10-19active
CRC-MRDN-005 Priya IversenMRN 602540460 / FSite 18 — Toronto2025-10-24active
CRC-MRDN-006 Theo O'ConnorMRN 602540563 / MSite 22 — Madrid2025-10-29active
CRC-MRDN-007 Sara TanakaMRN 602540666 / FSite 03 — Chicago2025-11-03active
CRC-MRDN-008 Antonio MarquezMRN 602540769 / MSite 09 — Munich2025-11-08active

Linked study

P2-CRC-D0918

ctDNA-guided adjuvant de-escalation

Recurrence-free survival, 24 mo · 87/160 enrolled

Sister cohorts in P2-CRC-D0918

Endpoints attached to this protocol

Cross-links