Cohort · P2-CRC-D0918Active studySynthetic mock data

ctDNA MRD-positive sub-cohort

Owner ML · last updated 2026-04-26

Size

64

Status

expanding

Inclusion criteria

2

Exclusion criteria

2

Definition

Inclusion

  • +Stage III CRC s/p curative resection
  • +Detectable ctDNA at week 4 post-op

Exclusion

  • Prior CRC malignancy
  • Inadequate surgical margin
expandingP2-CRC-D0918Owner MLLast updated 2026-04-26

Enrollment over time

032640w4w8w12w16w20w

From wk 0 (n=0) to wk 20 (n=64)

Subjects in cohort (10)

SubjectMRNAge / SexSiteEnrolledStatus
CRC-MRDP-001 Maria AlvarezMRN 602530048 / FSite 03 — Chicago2025-09-15withdrawn
CRC-MRDP-002 Henry MüllerMRN 602530151 / MSite 09 — Munich2025-09-20active
CRC-MRDP-003 Rachel SørensenMRN 602530254 / FSite 12 — Singapore2025-09-25active
CRC-MRDP-004 Robert AdebayoMRN 602530357 / MSite 14 — Boston2025-09-30active
CRC-MRDP-005 Priya IversenMRN 602530460 / FSite 18 — Toronto2025-10-05active
CRC-MRDP-006 Theo O'ConnorMRN 602530563 / MSite 22 — Madrid2025-10-10active
CRC-MRDP-007 Sara TanakaMRN 602530666 / FSite 03 — Chicago2025-10-15active
CRC-MRDP-008 Antonio MarquezMRN 602530769 / MSite 09 — Munich2025-10-20active
CRC-MRDP-009 Aisha HassanMRN 602530872 / FSite 12 — Singapore2025-10-25active
CRC-MRDP-010 Omar SinghMRN 602530975 / MSite 14 — Boston2025-10-30active

Linked study

P2-CRC-D0918

ctDNA-guided adjuvant de-escalation

Recurrence-free survival, 24 mo · 87/160 enrolled

Sister cohorts in P2-CRC-D0918

Endpoints attached to this protocol

Cross-links